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韩守法

发布日期:2017-04-26     浏览次数:次   

教授、博士生导师
办公室：beat365正版唯一官网化学生物学系卢嘉锡楼530
电话：（0592）2181728 （实验室）
电子邮箱：shoufa@xmu.edu.cn

个人简历：
博士（University of Toledo，2003）
硕士（北京科学院化学研究所,1999）
学士（北京大学,1996）
博士后（The Scripps Research Institute）

     研究兴趣：
基于有机小分子的疾病关联细胞器变化分析与功能调控，糖探针调控炎症反应与肿瘤免疫识别（有机、化学生物学专业招生）

近期主要代表论著：

  1. 1.Responsive hetero-organelle partition conferred fluorogenic sensing of mitochondrial depolarization; Zhongwei Xue, Hu Zhao, Jian Liu, Jiahuai Han, Shoufa Han*, Chem. Sci. 2017, 8, 1915-1921

  2. 2.Imaging lysosomal pH alteration in stressed cells with a sensitive ratiometric fluorescence sensor, Zhongwei Xue, Hu Zhao, Jian Liu, aJiahuai Han, Shoufa Han*, ACS Sensors. 2017, 2, 436-442

  3. 3.Redirecting immunity via covalently incorporated immunogenic sialic acid on the tumor cell surface, Bijuan Lin, Xuanjun Wu, Hu Zhao, Yunpeng Tian, Jian Liu, Jiahuai Han, and Shoufa Han*, Chem. Sci. 2016, 7, 3737-3741

  4. 4.A carbohydrate-grafted nanovesicle for fluorescence and acoustic imaging of tumors, Xuanjun Wu, Bijuan Lin, Mingzhu Yu, Jiahuai Han, Shoufa Han*, Chem. Sci. 2015, 6, 2002-2009

  5. 5.A sialic acid-targeted near-infrared theranostic for signal activation based intraoperative tumor ablation; Xuanjun Wu, Mingzhu Yu, Bijuan Lin, Hongjie Xing, Jiahuai Han, and Shoufa Han*, Chem. Sci. 2015, 6, 798-803

  6. 6.Optical Tracking of Phagocytosis with an Activatable Profluorophore Metabolically Incorporated into Bacterial Peptidoglycan; Yunpeng Tian, Mingzu Yu, Zhu Li, Jiahuai Han, Liu Yang*, Shoufa Han*, Anal. Chem., 2015, 87, 8381-8386

  7. 7.Lysosomal pH Decrease in Inflammatory Cells Used To Enable Activatable Imaging of Inflammation with a Sialic Acid Conjugated Profluorophore; Mingzhu Yu, Xuanjun Wu, Bijuan Lin, Jiahuai Han, Liu Yang, and Shoufa Han*, Anal. Chem., 2015, 87, 6688-6695

  8. 8.A self-referenced nanodosimeter for reaction based ratiometric detection of hypochlorous acid in living cells，Xuanjun Wu, Zhu Li, Yuhui Yang, Liu Yang, Jiahuai Han and Shoufa Han* Chem. Sci., 2013, 460-467

  9. 9.Rhodamine-deoxylactam functionalized poly[styrene-alter-(maleic acid)] as lysosome activatable probes for intraoperative detection of tumors，Zhu Li, Yunlong Song, Yuhui Yang, Liu Yang, Xiaohong Huang, Jiahuai Han and Shoufa Han*, Chem. Sci., 2012, 2, 2941-2948

  10. 10.Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking；　 Shoufa Han, Brian E. Collins, Per Bengtson, and James C. Paulson*, Nat. Chem. Biol., 2005,1, 93-97


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