郭晨云

发布日期:2013-03-10     浏览次数:次   

E-mail: guochy78@gmail.com

个人简历:
山西大学生物科学与技术学院生物化学理学学士(1996-2000);
山西大学生物技术研究所生物化学与分子生物学理学博士(2000-2005);
中科院上海药物研究所助理研究员(2005-2008);
美国马里兰大学化学与生物化学系博士后(2008-2010);
beat365正版唯一官网化学与化工学院化学生物化学系副教授(2010-)

     研究兴趣:
蛋白质和多肽的结构与功能研究

近期主要代表论著:

  1. C. Guo*, R.Godoy-Ruiz, V.Tugarinov, High resolution measurement of methyl 13C(m)-13C and 1H(m)-13C(m) residual dipolar couplings in large proteins. J. Am. Chem. Soc. 132:13984 (2010).

  2. C.Guo*, Y. Lian, Q, Liu, J. Liu, Y. Zhang, D. Lin, Soluble expression and characterization of a mouse epididymis- specific protein lipocalin6, Protein Expr. Puri, 69: 64 (2010)

  3. C. Guo*, V. Tugarinov, Selective 1H-13C NMR spectroscopy of methyl groups in residually protonated samples of large proteins, J. Biomol. NMR, 46:127 (2010).

  4. C. Guo*, C. Geng, V. Tugarinov,Selective backbone labeling of proteins using 1,2-13C2 -pyruvate as carbon source, J. Biomol. NMR. 44: 167(2009).

  5. C. Guo*, H. Diao, Y. Lian, H. Yu, H. Gao, Y. Zhang, D. Lin, Recombinant expression and characterization of an epididymis-specific antimicrobial peptide BIN1b / SPAG11E, J. Biotechnol., 139: 33 (2009)

  6. C. Guo*, D. Zhang, V. Tugarinov, A NMR experiment for simultaneous TROSY - based detection of amide and methyl groups in large proteins, J. Am. Chem. Soc. 130: 10872 (2008)

  7. C. Guo*, V. Tugarinov, Identification of HN-Methyl NOEs in large proteins using simultaneous amide-methyl TROSY-based Detection, J. Biomol. NMR, 43: 21 (2008)

  8. C. Guo*, Z. Li, J. Yuan, Preparation of an immunoadsorbent coupled with a recombinant antigen to remove anti-acetylcholine receptor antibodies in abnormal serum, J. Immunol. Method, 303:142 (2005)

  9. C. Guo*, Z. Li,?Y. Shi, et al, Intein-mediated fusion expression, high efficient refolding and one-step purification of gelonin toxin, Protein Expr. Puri., 37: 361 (2004)


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